Dynamin 1 antibody (AA 616-667) (Fluoro488)

Catalog No. ABIN7986547

The Rabbit Polyclonal anti-Dynamin 1 antibody is suitable to detect Dynamin 1 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for Dynamin 1 antibody (AA 616-667) (Fluoro488) (ABIN7986547)

Target: Dynamin 1 (DNM1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dynamin 1 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-Dynamin 1 Antibody (Fluoro488)

Binding Specificity: AA 616-667

Purpose: Anti-Dynamin 1/DNM1 Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Dynamin 1 recombinant protein (Position: W616-D667).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Dynamin 1

Target: Dynamin 1 (DNM1)

Alternative Name: DNM1

Background:

Background: Dynamin-1 is a protein that in humans is encoded by the DNM1 gene. This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene Full Name: dynamin 1

Gene ID: 1759

UniProt: Q05193

Pathways: Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling