DTNBP1 antibody (AA 1-351) (Fluoro488)

Catalog No. ABIN7986692

The Fluoro488-conjugated Rabbit Polyclonal anti-DTNBP1 antibody (ABIN7986692) specifically detects DTNBP1 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for DTNBP1 antibody (AA 1-351) (Fluoro488) (ABIN7986692)

Target: DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DTNBP1 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-DTNBP1 Antibody (Fluoro488)

Binding Specificity: AA 1-351

Purpose: Anti-Dysbindin/DTNBP1 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human Dysbindin,DTNBP1 shares 79.4%,78.6% amino acid (aa) sequence identity with mouse,rat Dysbindin,DTNBP1,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Dysbindin/DTNBP1 recombinant protein (Position: M1-S351). Human Dysbindin/DTNBP1 shares 79.4% and 78.6% amino acid (aa) sequence identity with mouse and rat Dysbindin/DTNBP1, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for DTNBP1

Target: DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))

Alternative Name: DTNBP1

Background:

Background: This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this gene are associated with Hermansky-Pudlak syndrome type 7. This gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Gene Full Name: dystrobrevin binding protein 1

Gene ID: 84062

UniProt: Q96EV8

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling