DTNBP1 antibody (AA 1-351)

Catalog No. ABIN7986700

The Rabbit Polyclonal anti-DTNBP1 antibody is suitable to detect DTNBP1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and FACS.

Quick Overview for DTNBP1 antibody (AA 1-351) (ABIN7986700)

Target: DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DTNBP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-DTNBP1 Antibody

Binding Specificity: AA 1-351

Purpose: Anti-Dysbindin/DTNBP1 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human Dysbindin,DTNBP1 shares 79.4%,78.6% amino acid (aa) sequence identity with mouse,rat Dysbindin,DTNBP1,respectively.

Characteristics: Anti-Dysbindin/DTNBP1 Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Dysbindin/DTNBP1 recombinant protein (Position: M1-S351). Human Dysbindin/DTNBP1 shares 79.4% and 78.6% amino acid (aa) sequence identity with mouse and rat Dysbindin/DTNBP1, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DTNBP1

Target: DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))

Alternative Name: DTNBP1

Background:

Background: This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this gene are associated with Hermansky-Pudlak syndrome type 7. This gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Gene Full Name: dystrobrevin binding protein 1

Molecular Weight: 50 kDa

Gene ID: 84062

UniProt: Q96EV8

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling