Ectodysplasin A antibody (AA 30-391) (HRP)

Catalog No. ABIN7987128

This Rabbit Polyclonal antibody specifically detects Ectodysplasin A in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for Ectodysplasin A antibody (AA 30-391) (HRP) (ABIN7987128)

Target: Ectodysplasin A (EDA)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ectodysplasin A antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Ectodysplasin A Antibody (HRP)

Binding Specificity: AA 30-391

Purpose: Anti-EDA Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human EDA shares 95% amino acid (aa) sequence identity with mouse EDA.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human EDA recombinant protein (Position: A30-S391). Human EDA shares 95% amino acid (aa) sequence identity with mouse EDA.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Ectodysplasin A

Target: Ectodysplasin A (EDA)

Alternative Name: EDA

Background:

Background: Ectodysplasin-A is a protein that in humans is encoded by the EDA gene. It is mapped to Xq13.1. The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia.

Gene Full Name: ectodysplasin A

Sequence Similarities: Belongs to the tumor necrosis factor family.

Gene ID: 1896

UniProt: Q92838

Pathways: Tube Formation