Ectodysplasin A antibody (AA 30-391)

Catalog No. ABIN7987132

The Rabbit Polyclonal anti-Ectodysplasin A antibody is suitable to detect Ectodysplasin A in samples from Human. It has been validated for WB.

Quick Overview for Ectodysplasin A antibody (AA 30-391) (ABIN7987132)

Target: Ectodysplasin A (EDA)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ectodysplasin A antibody is un-conjugated

Application: Western Blotting (WB)

Grade: Carrier-free

Product Details anti-Ectodysplasin A Antibody

Binding Specificity: AA 30-391

Purpose: Anti-EDA Antibody

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human EDA shares 95% amino acid (aa) sequence identity with mouse EDA.

Characteristics: Anti-EDA Antibody. Tested in WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human EDA recombinant protein (Position: A30-S391). Human EDA shares 95% amino acid (aa) sequence identity with mouse EDA.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Ectodysplasin A

Target: Ectodysplasin A (EDA)

Alternative Name: EDA

Background:

Background: Ectodysplasin-A is a protein that in humans is encoded by the EDA gene. It is mapped to Xq13.1. The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia.

Gene Full Name: ectodysplasin A

Sequence Similarities: Belongs to the tumor necrosis factor family.

Molecular Weight: 43 kDa

Gene ID: 1896

UniProt: Q92838

Pathways: Tube Formation