NFAM1 antibody (PE-Cy7)

Catalog No. ABIN749046

The PE-Cy7-conjugated Rabbit Polyclonal anti-NFAM1 antibody (ABIN749046) specifically detects NFAM1 in WB. The antibody is reactive with Human, Mouse, Rat and Pig samples.

Quick Overview for NFAM1 antibody (PE-Cy7) (ABIN749046)

Target: NFAM1 (NFAT Activating Protein with ITAM Motif 1 (NFAM1))

Reactivity: Human, Mouse, Rat, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFAM1 antibody is conjugated to PE-Cy7

Application: Western Blotting (WB)

Product Details anti-NFAM1 Antibody (PE-Cy7)

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NFAM1

Isotype: IgG

Application Details

Application Notes: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NFAM1

Target: NFAM1 (NFAT Activating Protein with ITAM Motif 1 (NFAM1))

Alternative Name: NFAM1

Background:

Synonyms: CNAIP, bK126B4.4, NFAT activation molecule 1, Calcineurin/NFAT-activating ITAM-containing protein, NFAT-activating protein with ITAM motif 1, NFAM1

Background: May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross-linking.

Molecular Weight: 25/30kDa

Gene ID: 150372

UniProt: Q8NET5