EVC2 antibody (AA 379-901) (Cy3)

Catalog No. ABIN7987356

This Rabbit Polyclonal antibody specifically detects EVC2 in FACS. It exhibits reactivity toward Mouse and Rat.

Quick Overview for EVC2 antibody (AA 379-901) (Cy3) (ABIN7987356)

Target: EVC2 (Ellis Van Creveld Syndrome 2 (EVC2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EVC2 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-EVC2 Antibody (Cy3)

Binding Specificity: AA 379-901

Purpose: Anti-EVC2 Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Mouse EVC2 shares 76.6% amino acid (aa) sequence identity with human EVC2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse EVC2 recombinant protein (Position: Q379-D901). Mouse EVC2 shares 76.6% amino acid (aa) sequence identity with human EVC2.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for EVC2

Target: EVC2 (Ellis Van Creveld Syndrome 2 (EVC2))

Alternative Name: EVC2

Background:

Background: Involved in smoothened signaling pathway. Located in ciliary membrane and nucleus. Part of plasma membrane protein complex. Is expressed in several structures, including bone, heart, jaw, nose, and paranasal sinus. Used to study Ellis-Van Creveld syndrome. Human ortholog(s) of this gene implicated in Ellis-Van Creveld syndrome and Weyers acrofacial dysostosis. Orthologous to human EVC2 (EvC ciliary complex subunit 2).

Gene Full Name: EvC ciliary complex subunit 2

Gene ID: 68525

UniProt: Q8K1G2

Pathways: Hedgehog Signaling