EVC2 antibody (AA 379-901) (HRP)

Catalog No. ABIN7987361

The HRP-conjugated Rabbit Polyclonal anti-EVC2 antibody (ABIN7987361) specifically detects EVC2 in ELISA, IHC and WB. The antibody is reactive with Mouse and Rat samples.

Quick Overview for EVC2 antibody (AA 379-901) (HRP) (ABIN7987361)

Target: EVC2 (Ellis Van Creveld Syndrome 2 (EVC2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EVC2 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-EVC2 Antibody (HRP)

Binding Specificity: AA 379-901

Purpose: Anti-EVC2 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Mouse EVC2 shares 76.6% amino acid (aa) sequence identity with human EVC2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse EVC2 recombinant protein (Position: Q379-D901). Mouse EVC2 shares 76.6% amino acid (aa) sequence identity with human EVC2.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for EVC2

Target: EVC2 (Ellis Van Creveld Syndrome 2 (EVC2))

Alternative Name: EVC2

Background:

Background: Involved in smoothened signaling pathway. Located in ciliary membrane and nucleus. Part of plasma membrane protein complex. Is expressed in several structures, including bone, heart, jaw, nose, and paranasal sinus. Used to study Ellis-Van Creveld syndrome. Human ortholog(s) of this gene implicated in Ellis-Van Creveld syndrome and Weyers acrofacial dysostosis. Orthologous to human EVC2 (EvC ciliary complex subunit 2).

Gene Full Name: EvC ciliary complex subunit 2

Gene ID: 68525

UniProt: Q8K1G2

Pathways: Hedgehog Signaling