EVC2 antibody (AA 379-901)

Catalog No. ABIN7987365

This Rabbit Polyclonal antibody specifically detects EVC2 in ELISA, IHC, WB and IF. It exhibits reactivity toward Mouse and Rat.

Quick Overview for EVC2 antibody (AA 379-901) (ABIN7987365)

Target: EVC2 (Ellis Van Creveld Syndrome 2 (EVC2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EVC2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Grade: Carrier-free

Product Details anti-EVC2 Antibody

Binding Specificity: AA 379-901

Purpose: Anti-EVC2 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Mouse EVC2 shares 76.6% amino acid (aa) sequence identity with human EVC2.

Characteristics: Anti-EVC2 Antibody. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse EVC2 recombinant protein (Position: Q379-D901). Mouse EVC2 shares 76.6% amino acid (aa) sequence identity with human EVC2.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Rat Immunofluorescence, 5 μg/mL, Rat ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for EVC2

Target: EVC2 (Ellis Van Creveld Syndrome 2 (EVC2))

Alternative Name: EVC2

Background:

Background: Involved in smoothened signaling pathway. Located in ciliary membrane and nucleus. Part of plasma membrane protein complex. Is expressed in several structures, including bone, heart, jaw, nose, and paranasal sinus. Used to study Ellis-Van Creveld syndrome. Human ortholog(s) of this gene implicated in Ellis-Van Creveld syndrome and Weyers acrofacial dysostosis. Orthologous to human EVC2 (EvC ciliary complex subunit 2).

Gene Full Name: EvC ciliary complex subunit 2

Molecular Weight: 153 kDa

Gene ID: 68525

UniProt: Q8K1G2

Pathways: Hedgehog Signaling