EOMES antibody (AA 310-532) (PE)

Catalog No. ABIN7987937

The PE-conjugated Rabbit Polyclonal anti-EOMES antibody (ABIN7987937) specifically detects EOMES in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for EOMES antibody (AA 310-532) (PE) (ABIN7987937)

Target: EOMES (Eomesodermin (EOMES))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EOMES antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-EOMES Antibody (PE)

Binding Specificity: AA 310-532

Purpose: Anti-TBR2/Eomes Antibody PE Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human TBR2/Eomes recombinant protein (Position: T310-D532).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for EOMES

Target: EOMES (Eomesodermin (EOMES))

Alternative Name: EOMES

Background:

Background: Eomesodermin also known as T-box brain protein 2 (Tbr2) is a protein that in humans is encoded by the EOMES gene. This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants.

Gene Full Name: eomesodermin

Gene ID: 8320

UniProt: O95936

Pathways: Stem Cell Maintenance