EDEM1 antibody (AA 124-657)

Catalog No. ABIN7988324

The Rabbit Polyclonal anti-EDEM1 antibody (ABIN7988324) specifically detects EDEM1 in WB, ELISA and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for EDEM1 antibody (AA 124-657) (ABIN7988324)

Target: EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EDEM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-EDEM1 Antibody

Binding Specificity: AA 124-657

Purpose: Anti-EDEM1 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human EDEM1 shares 96.6% amino acid (aa) sequence identity with mouse EDEM1.

Characteristics: Anti-EDEM1 Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human EDEM1 recombinant protein (Position: P124-I657). Human EDEM1 shares 96.6% amino acid (aa) sequence identity with mouse EDEM1.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for EDEM1

Target: EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))

Alternative Name: EDEM1

Background:

Background: Enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity and misfolded protein binding activity. Involved in positive regulation of retrograde protein transport, ER to cytosol, protein targeting to ER, and proteolysis involved in protein catabolic process. Located in aggresome and endoplasmic reticulum quality control compartment.

Gene Full Name: ER degradation enhancing alpha-mannosidase like protein 1

Molecular Weight: 66 kDa

Gene ID: 9695

UniProt: Q92611

Pathways: ER-Nucleus Signaling