EPB41L1 antibody (AA 691-881) (Biotin)

Catalog No. ABIN7988380

The Rabbit Polyclonal anti-EPB41L1 antibody is suitable to detect EPB41L1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for EPB41L1 antibody (AA 691-881) (Biotin) (ABIN7988380)

Target: EPB41L1 (erythrocyte Membrane Protein Band 4.1-Like 1 (EPB41L1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPB41L1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-EPB41L1 Antibody (Biotin)

Binding Specificity: AA 691-881

Purpose: Anti-EPB41L1 Antibody Biotin Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human EPB41L1 shares 91% amino acid (aa) sequence identity with both mouse,rat EPB41L1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human EPB41L1 recombinant protein (Position: Q691-S881). Human EPB41L1 shares 91% amino acid (aa) sequence identity with both mouse and rat EPB41L1.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for EPB41L1

Target: EPB41L1 (erythrocyte Membrane Protein Band 4.1-Like 1 (EPB41L1))

Alternative Name: EPB41L1

Background:

Background: Band 4.1-like protein 1 is a protein that in humans is encoded by the EPB41L1 gene. This gene is mapped to 20q11.23. It is found that a heterozygous missense mutation in the EPB41L1 gene causing nonsyndromic intellectual disability. This gene may function to confer stability and plasticity to neuronal membrane via multiple interactions, including the spectrin-actin-based cytoskeleton, integral membrane channels and membrane-associated guanylate kinases. What's more, EPB41L1 is a multifunctional protein that mediates interactions between the erythrocyte cytoskeleton and the overlying plasma membrane.

Gene Full Name: erythrocyte membrane protein band 4.1 like 1

Sequence Similarities: Contains 1 FERM domain.

Gene ID: 2036

UniProt: Q9H4G0