ETV4 antibody (N-Term) (HRP)

Catalog No. ABIN7988551

The Rabbit Polyclonal anti-ETV4 antibody is suitable to detect ETV4 in samples from Human and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for ETV4 antibody (N-Term) (HRP) (ABIN7988551)

Target: ETV4 (Ets Variant 4 (ETV4))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ETV4 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-ETV4 Antibody (HRP)

Binding Specificity: N-Term

Purpose: Anti-Pea3/ETV4 Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse sequence by seven amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Pea3, different from the related mouse sequence by seven amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ETV4

Target: ETV4 (Ets Variant 4 (ETV4))

Alternative Name: ETV4

Background:

Background: ETS translocation variant 4  (ETV4), also known as polyoma enhancer activator 3  (PEA3), or E1AF, is a member of the PEA3 subfamily of Ets transcription factors. It is mapped to 17q21.31. E1AF can activate the promoters of various matrix metalloproteinases, genes whose expression is associated with tumor cell invasion and metastasis, by 10 to 20 fold. Pea3 is detected in cells of epithelial and fibroblastic origin. It is also a transcriptional activator that binds to the enhancer of the adenovirus E1A gene.

Gene Full Name: ETS variant transcription factor 4

Gene ID: 2118

UniProt: P43268