ETV4 antibody (N-Term)

Catalog No. ABIN7988555

The Rabbit Polyclonal anti-ETV4 antibody (ABIN7988555) specifically detects ETV4 in WB. The antibody is reactive with Human and Rat samples.

Quick Overview for ETV4 antibody (N-Term) (ABIN7988555)

Target: ETV4 (Ets Variant 4 (ETV4))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ETV4 antibody is un-conjugated

Application: Western Blotting (WB)

Grade: Carrier-free

Product Details anti-ETV4 Antibody

Binding Specificity: N-Term

Purpose: Anti-Pea3/ETV4 Antibody

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse sequence by seven amino acids.

Characteristics: Anti-Pea3/ETV4 Antibody. Tested in WB applications. This antibody reacts with Human, Rat.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Pea3, different from the related mouse sequence by seven amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Rat

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ETV4

Target: ETV4 (Ets Variant 4 (ETV4))

Alternative Name: ETV4

Background:

Background: ETS translocation variant 4  (ETV4), also known as polyoma enhancer activator 3  (PEA3), or E1AF, is a member of the PEA3 subfamily of Ets transcription factors. It is mapped to 17q21.31. E1AF can activate the promoters of various matrix metalloproteinases, genes whose expression is associated with tumor cell invasion and metastasis, by 10 to 20 fold. Pea3 is detected in cells of epithelial and fibroblastic origin. It is also a transcriptional activator that binds to the enhancer of the adenovirus E1A gene.

Gene Full Name: ETS variant transcription factor 4

Molecular Weight: 68 kDa

Gene ID: 2118

UniProt: P43268