ETV6 antibody (AA 327-448) (HRP)

Catalog No. ABIN7988573

The HRP-conjugated Rabbit Polyclonal anti-ETV6 antibody (ABIN7988573) specifically detects ETV6 in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ETV6 antibody (AA 327-448) (HRP) (ABIN7988573)

Target: ETV6 (Ets Variant 6 (ETV6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ETV6 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-ETV6 Antibody (HRP)

Binding Specificity: AA 327-448

Purpose: Anti-ETV6/Tel Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human ETV6/Tel recombinant protein (Position: E327-Q448).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ETV6

Target: ETV6 (Ets Variant 6 (ETV6))

Alternative Name: ETV6

Background:

Background: Transcription factor ETV6 is a protein that in humans is encoded by the ETV6 gene. This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.

Gene Full Name: ETS variant transcription factor 6

Gene ID: 2120

UniProt: P41212