EIF1 antibody (AA 2-10) (PE)

Catalog No. ABIN7988665

The Rabbit Polyclonal anti-EIF1 antibody is suitable to detect EIF1 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for EIF1 antibody (AA 2-10) (PE) (ABIN7988665)

Target: EIF1 (Eukaryotic Translation Initiation Factor 1 (EIF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-EIF1 Antibody (PE)

Binding Specificity: AA 2-10

Purpose: Anti-EIF1 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human EIF1 recombinant protein (Position: S2-D10⁶).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for EIF1

Target: EIF1 (Eukaryotic Translation Initiation Factor 1 (EIF1))

Alternative Name: EIF1

Background:

Background: Eukaryotic translation initiation factor 1 (eIF1) is a protein that in humans is encoded by the EIF1 gene. It is related to yeast SUI1. In mammalian cells, translation is controlled at the level of polypeptide chain initiation by initiation factors. Eukaryotic translation initiation factor 1 (eIF1) is crucial for the scanning process in vitro. During the scanning process, eIF1 is a component of a complex involved in recognition of the initiator codon. Translation is also initiated by the role of eIF1 in regulating the activity of ribosomal subunits 43S, 48S and 40S. eIF1 enables 43S ribosomal complexes to discern between cognate and near-cognate initiation codons, sensing the nucleotide content of initiation codons. It is also a promotor, along with eukar-yotic translation initiation factor 1A (eIF1A), for assembly of 48S ribosomal complexes at the initiation codon of a conventional capped mRNA. In addition, eIF1 and eIF1A, together with eukaryotic translation initiation factor 5 (eIF5), function in the formation of stable 40S ribosomal preinitiation complexes.

Gene Full Name: eukaryotic translation initiation factor 1

Gene ID: 10209

UniProt: P41567