ETF1 antibody (AA 9-342) (Fluoro550)

Catalog No. ABIN7989191

The Fluoro550-conjugated Mouse Monoclonal anti-ETF1 antibody (Clone 3 E5) (ABIN7989191) specifically detects ETF1 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ETF1 antibody (AA 9-342) (Fluoro550) (ABIN7989191)

Target: ETF1 (Eukaryotic Translation Termination Factor 1 (ETF1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This ETF1 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Clone: 3 E5

Product Details anti-ETF1 Antibody (Fluoro550)

Binding Specificity: AA 9-342

Purpose: Anti-eRF1/ETF1 Antibody (monoclonal, 3E5) Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human eRF1/ETF1 recombinant protein (Position: D9-K342).

Isotype: IgG2b

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ETF1

Target: ETF1 (Eukaryotic Translation Termination Factor 1 (ETF1))

Alternative Name: ETF1

Background:

Background: Eukaryotic translation termination factor 1 (eRF1), also known asTB3-1, is a protein that in humans is encoded by the ETF1 gene. It is mapped to 5q31.2. This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in ing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X.

Gene Full Name: eukaryotic translation termination factor 1

Gene ID: 2107

UniProt: P62495