DIS3 antibody (AA 62-304) (Fluoro488)

Catalog No. ABIN7989311

The Fluoro488-conjugated Rabbit Polyclonal anti-DIS3 antibody (ABIN7989311) specifically detects DIS3 in FACS. The antibody is reactive with Human and Rat samples.

Quick Overview for DIS3 antibody (AA 62-304) (Fluoro488) (ABIN7989311)

Target: DIS3 (Exosome Complex Exonuclease RRP44 (DIS3))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DIS3 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-DIS3 Antibody (Fluoro488)

Binding Specificity: AA 62-304

Purpose: Anti-DIS3 Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human DIS3 recombinant protein (Position: Q62-A304).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for DIS3

Target: DIS3 (Exosome Complex Exonuclease RRP44 (DIS3))

Alternative Name: DIS3

Background:

Background: Exosome complex exonuclease RRP44 or Dis3 is an enzyme that in humans is encoded by the DIS3 gene. Its protein product is an RNase enzyme homologous to the yeast protein Rrp44, and can be part of the exosome complex in the nucleus of eukaryotic cells. By genomic sequence analysis, this gene is mapped to chromosome 13q21-q22. Expression of human DIS3 could partially complement Dis3 depletion in yeast.

Gene Full Name: DIS3 exosome endoribonuclease and 3'-5' exoribonuclease

UniProt: Q9Y2L1