Ezrin antibody (N-Term) (HRP)
Quick Overview for Ezrin antibody (N-Term) (HRP) (ABIN7989437)
Target
See all Ezrin (EZR) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Purpose
- Anti-Ezrin/EZR Antibody HRP Conjugated
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins.
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Purification
- Immunogen affinity purified.
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Immunogen
- A synthetic peptide corresponding to a sequence at the N-terminus of human Ezrin/EZR, which shares 85.7% amino acid (aa) sequence identity with mouse and rat EZR.
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Isotype
- IgG
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Application Notes
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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Storage
- -20 °C
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Storage Comment
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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Expiry Date
- 12 months
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- Ezrin (EZR)
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Alternative Name
- EZR
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Background
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Background: Ezrin also known as cytovillin or villin-2 is a protein that in humans is encoded by the EZR gene. The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.
Gene Full Name: ezrin
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Gene ID
- 7430
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UniProt
- P15311
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Pathways
- Maintenance of Protein Location
Target
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