F11R antibody (N-Term) (Fluoro550)

Catalog No. ABIN7989500

The Fluoro550-conjugated Rabbit Polyclonal anti-F11R antibody (ABIN7989500) specifically detects F11R in FACS. The antibody is reactive with Human samples.

Quick Overview for F11R antibody (N-Term) (Fluoro550) (ABIN7989500)

Target: F11R (F11 Receptor (F11R))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This F11R antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-F11R Antibody (Fluoro550)

Binding Specificity: N-Term

Purpose: Anti-JAM-A/F11R Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human JAM-A/F11R, which shares 75% and 80% amino acid (aa) sequence identity with mouse and rat JAM-A/F11R, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for F11R

Target: F11R (F11 Receptor (F11R))

Alternative Name: F11R

Background:

Background: Junctional adhesion molecule A is a protein that in humans is encoded by the F11R gene. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

Gene Full Name: F11 receptor

Gene ID: 50848

UniProt: Q9Y624

Pathways: Cell-Cell Junction Organization