FAF1 antibody (AA 91-650) (Cy3)

Catalog No. ABIN7989674

The Cy3-conjugated Rabbit Polyclonal anti-FAF1 antibody (ABIN7989674) specifically detects FAF1 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for FAF1 antibody (AA 91-650) (Cy3) (ABIN7989674)

Target: FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAF1 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-FAF1 Antibody (Cy3)

Binding Specificity: AA 91-650

Purpose: Anti-FAF1 Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human FAF1 recombinant protein (Position: R91-E650).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for FAF1

Target: FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))

Alternative Name: FAF1

Background:

Background: Fas-associated factor-1(FAF1) is a Fas-binding pro-apoptotic protein that is a component of the death-inducing signaling complex in Fas-mediated apoptosis. FAF1 is involved in negative regulation of NF-kappaB activation. In addition to the previously known function as a component of the Fas death-inducing signaling complex, i.e. NF-kappaB activity suppressor by cytoplasmic retention of NF-kappaB p65 via physical interaction. hFAF1 was expressed abundantly in testis, skeletal muscle, and heart as 2.8 kb mRNA. Polyclonal antibody against hFAF1 detected 74 kD protein, a deduced protein size from the ORF and 40 kD protein in some cell lines.

Gene Full Name: Fas associated factor 1

Gene ID: 11124

UniProt: Q9UNN5

Pathways: Maintenance of Protein Location