FABP4 antibody (AA 2-132) (HRP)

Catalog No. ABIN7989943

The Rabbit Polyclonal anti-FABP4 antibody is suitable to detect FABP4 in samples from Mouse and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for FABP4 antibody (AA 2-132) (HRP) (ABIN7989943)

Target: FABP4 (Fatty Acid Binding Protein 4, Adipocyte (FABP4))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FABP4 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-FABP4 Antibody (HRP)

Binding Specificity: AA 2-132

Purpose: Anti-FABP4 Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived rat FABP4 recombinant protein (Position: C2-A132). Rat FABP4 shares 88.5%,93.9% amino acid (aa) sequence identity with human,mouse FABP4,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived rat FABP4 recombinant protein (Position: C2-A132). Rat FABP4 shares 88.5% and 93.9% amino acid (aa) sequence identity with human and mouse FABP4, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FABP4

Target: FABP4 (Fatty Acid Binding Protein 4, Adipocyte (FABP4))

Alternative Name: Fabp4

Background:

Background: Fatty acid binding proteins (FABPs) are small cytoplasmic proteins that are expressed in a highly tissue-specific manner and bind to fatty acids such as oleic and retinoic acid. Adipocyte fatty-acid-binding protein, aP2 (FABP4) is expressed in adipocytes and macrophages, and integrates inflammatory and metabolic responses. Studies in aP2-deficient mice have shown that this lipid chaperone has a significant role in several aspects of metabolic syndrome, including type 2 diabetes and atherosclerosis. It regulates allergic airway inflammation and may provide a link between fatty acid metabolism and asthma.

Gene Full Name: Fatty acid-binding protein, adipocyte

Gene ID: 79451

UniProt: P70623

Pathways: Brown Fat Cell Differentiation