FCAR antibody (Biotin)

Catalog No. ABIN7990103

The Biotin-conjugated Rabbit Polyclonal anti-FCAR antibody (ABIN7990103) specifically detects FCAR in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for FCAR antibody (Biotin) (ABIN7990103)

Target: FCAR (Fc Fragment of IgA, Receptor For (FCAR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FCAR antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-FCAR Antibody (Biotin)

Purpose: Anti-CD89/FCAR Antibody Biotin Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle of human CD89.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FCAR

Target: FCAR (Fc Fragment of IgA, Receptor For (FCAR))

Alternative Name: FCAR

Background:

Background: FCAR, Receptor for Fc fragment of IGA, is also known as CD89. Human Fc-alpha receptor (FCAR) is present on a number of cell types, including neutrophils, monocytes, macrophages, and eosinophils. FCAR interacts with aggregated IgAs, such as IgA coated on the surface of an invading microorganism, and mediates several immunologic defense processes such as phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. FCAR is a glycoprotein of 50 to 100 kD, with diversity on different cell types. FCAR is mapped to 19q13.4. Human COS cells transfected with FCAR cDNA bind to IgA, but not IgG.

Gene Full Name: Fc alpha receptor

Gene ID: 2204

UniProt: P24071