FERMT2 antibody (AA 1-650) (APC)

Catalog No. ABIN7990264

The Rabbit Polyclonal anti-FERMT2 antibody is suitable to detect FERMT2 in samples from Human. It has been validated for FACS.

Quick Overview for FERMT2 antibody (AA 1-650) (APC) (ABIN7990264)

Target: FERMT2 (Fermitin Family Member 2 (FERMT2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FERMT2 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-FERMT2 Antibody (APC)

Binding Specificity: AA 1-650

Purpose: Anti-Kindlin 2/FERMT2 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Kindlin 2/FERMT2 recombinant protein (Position: M1-I650).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for FERMT2

Target: FERMT2 (Fermitin Family Member 2 (FERMT2))

Alternative Name: FERMT2

Background:

Background: Fermitin family homolog 2 (FERMT2) also known as pleckstrin homology domain-containing family C member 1 (PLEKHC1) or kindlin-2 is a protein that in humans is encoded by the FERMT2 gene. Enables several functions, including actin binding activity, phosphatidylinositol-3,4,5-trisphosphate binding activity, and type I transforming growth factor beta receptor binding activity. Involved in several processes, including cell surface receptor signaling pathway, positive regulation of cell differentiation, and positive regulation of cellular component biogenesis. Acts upstream of or within cell adhesion and protein localization to cell junction. Located in cytosol, focal adhesion, and nucleoplasm. Is extrinsic component of cytoplasmic side of plasma membrane. Part of adherens junction and plasma membrane. Biomarker of acute myeloid leukemia.

Gene Full Name: FERM domain containing kindlin 2

Gene ID: 10979

UniProt: Q96AC1

Pathways: Cell-Cell Junction Organization