FGF15 antibody (AA 26-218) (Fluoro488)

Catalog No. ABIN7990457

The Fluoro488-conjugated Rabbit Polyclonal anti-FGF15 antibody (ABIN7990457) specifically detects FGF15 in FACS. The antibody is reactive with Rat and Mouse samples.

Quick Overview for FGF15 antibody (AA 26-218) (Fluoro488) (ABIN7990457)

Target: FGF15 (Fibroblast Growth Factor 15 (FGF15))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF15 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-FGF15 Antibody (Fluoro488)

Binding Specificity: AA 26-218

Purpose: Anti-Fgf19(Fgf15) Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived rat Fgf19(Fgf15) recombinant protein (Position: R26-K218). Rat Fgf19(Fgf15) shares 53.2%,96.4% amino acid (aa) sequence identity with human,mouse FGF19,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived rat Fgf19(Fgf15) recombinant protein (Position: R26-K218). Rat Fgf19(Fgf15) shares 53.2% and 96.4% amino acid (aa) sequence identity with human and mouse FGF19, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for FGF15

Target: FGF15 (Fibroblast Growth Factor 15 (FGF15))

Alternative Name: Fgf19(Fgf15)

Background:

Background: FGF15/19 refers to two orthologous fibroblast growth factors which share 50 % aminoacid identity and have similar functions. FGF15 was described in the mouse, FGF19 was found in humans and other species. They share physiological functions and so are often referred to as FGF15/19 or as FGF15/FGF19. They were first described in developing fetal brain. They are now known to be produced in the ileum, and under certain circumstances in the liver and biliary tree. It is thought their principal function is in response to bile acid absorption occurring after meals. FGF15 and FGF19 have similar roles in regulating bile acid synthesis and also glucose metabolism in the liver.

Gene Full Name: fibroblast growth factor 19

Gene ID: 170582, 14170

UniProt: Q8VI81