FLNB antibody (AA 397-701) (PE)

Catalog No. ABIN7990905

This Mouse Monoclonal antibody specifically detects FLNB in FACS. It exhibits reactivity toward Human.

Quick Overview for FLNB antibody (AA 397-701) (PE) (ABIN7990905)

Target: FLNB (Filamin B, beta (FLNB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FLNB antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: 11E2D2

Product Details anti-FLNB Antibody (PE)

Binding Specificity: AA 397-701

Purpose: Anti-Filamin B/FLNB Antibody (monoclonal, 11E2D2) PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Filamin B/FLNB recombinant protein (Position: Q397-D701).

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for FLNB

Target: FLNB (Filamin B, beta (FLNB))

Alternative Name: FLNB

Background:

Background: Filamin B, beta (FLNB), also known as Filamin B, beta (truncated actin binding protein 278 homolog), is a cytoplasmic protein which in humans is encoded by the FLNB gene. This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3, boomerang dysplasia, autosomal dominant Larsen syndrome, and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Gene Full Name: filamin B

Gene ID: 2317

UniProt: O75369

Pathways: Maintenance of Protein Location