Fission 1 antibody (AA 18-152) (PE)

Catalog No. ABIN7990938

This Rabbit Polyclonal antibody specifically detects Fission 1 in FACS. It exhibits reactivity toward Human and Rat.

Quick Overview for Fission 1 antibody (AA 18-152) (PE) (ABIN7990938)

Target: Fission 1 (FIS1)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fission 1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-Fission 1 Antibody (PE)

Binding Specificity: AA 18-152

Purpose: Anti-TTC11/FIS1 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TTC11/FIS1 recombinant protein (Position: E18-S152).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Fission 1

Target: Fission 1 (FIS1)

Alternative Name: FIS1

Background:

Background: Mitochondrial fission 1 protein (FIS1) is a protein that in humans is encoded by the FIS1 gene on chromosome 7. It is mapped to 7q22.1. The balance between fission and fusion regulates the morphology of mitochondria. TTC11 is a component of a mitochondrial complex that promotes mitochondrial fission. Its role in mitochondrial fission thus implicates it in the regulation of mitochondrial morphology, the cell cycle, and apoptosis. By extension, the protein is involved in associated diseases, including neurodegenerative diseases and cancers.

Gene Full Name: fission, mitochondrial 1

Gene ID: 51024

UniProt: Q9Y3D6

Pathways: Positive Regulation of Endopeptidase Activity