FSHR antibody (AA 18-187) (Fluoro647)

Catalog No. ABIN7991280

This Rabbit Polyclonal antibody specifically detects FSHR in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for FSHR antibody (AA 18-187) (Fluoro647) (ABIN7991280)

Target: FSHR (Follicle Stimulating Hormone Receptor (FSHR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FSHR antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-FSHR Antibody (Fluoro647)

Binding Specificity: AA 18-187

Purpose: Anti-FSH Receptor/FSHR Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived human FSH Receptor recombinant protein (Position: C18-N187). Human FSH Receptor shares 91.2%,90% amino acid (aa) sequence identity with mouse,rat FSH Receptor,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human FSH Receptor recombinant protein (Position: C18-N187). Human FSH Receptor shares 91.2% and 90% amino acid (aa) sequence identity with mouse and rat FSH Receptor, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for FSHR

Target: FSHR (Follicle Stimulating Hormone Receptor (FSHR))

Alternative Name: FSHR

Background:

Background: The follicle-stimulating hormone receptor or FSH receptor (FSHR) is a transmembrane receptor that interacts with the follicle-stimulating hormone (FSH) and represents a G protein-coupled receptor (GPCR). This FSHR gene is mapped to chromosome 2p21 by fluorescence in situ hybridization. The protein encoded by this gene belongs to family 1 of G-protein coupled receptors. It is the receptor for follicle stimulating hormone and functions in gonad development. Mutations in this gene cause ovarian dysgenesis type 1, and also ovarian hyperstimulation syndrome. Alternative splicing results in multiple transcript variants.

Gene Full Name: follicle stimulating hormone receptor

Gene ID: 2492

UniProt: P23945

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Platelet-derived growth Factor Receptor Signaling