FLCN antibody (AA 8-551) (APC)

Catalog No. ABIN7991311

The Rabbit Polyclonal anti-FLCN antibody is suitable to detect FLCN in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for FLCN antibody (AA 8-551) (APC) (ABIN7991311)

Target: FLCN (Folliculin (FLCN))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLCN antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-FLCN Antibody (APC)

Binding Specificity: AA 8-551

Purpose: Anti-FLCN Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human FLCN recombinant protein (Position: C8-K551).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for FLCN

Target: FLCN (Folliculin (FLCN))

Alternative Name: FLCN

Target Type: Amino Acid

Background:

Background: Folliculin also known as FLCN, Birt-Hogg-Dubé syndrome protein or FLCN_HUMAN is a protein that in humans is associated with Birt-Hogg-Dubé syndrome and hereditary spontaneous pneumothorax. It is encoded by the Folliculin (FLCN) gene (alias BHD, FLCL) that acts as a tumor suppressor gene. It is mapped to 17p11.2. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Gene Full Name: folliculin

Gene ID: 201163

UniProt: Q8NFG4

Pathways: Cell-Cell Junction Organization