FOXP3 antibody (AA 27-337) (Cy3)

Catalog No. ABIN7991591

The Cy3-conjugated Rabbit Polyclonal anti-FOXP3 antibody (ABIN7991591) specifically detects FOXP3 in FACS. The antibody is reactive with Human samples.

Quick Overview for FOXP3 antibody (AA 27-337) (Cy3) (ABIN7991591)

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXP3 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-FOXP3 Antibody (Cy3)

Binding Specificity: AA 27-337

Purpose: Anti-FOXP3 Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human FOXP3 recombinant protein (Position: R27-R337).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for FOXP3

Target: FOXP3 (Forkhead Box P3 (FOXP3))

Alternative Name: FOXP3

Background:

Background: FOXP3(forkhead box P3) is a protein involved in immune system responses. The human FOXP3 genes contain 11 coding exons. Exon-intron boundaries are identical across the coding regions of the mouse and human genes. By genomic sequence analysis, the FOXP3 gene maps to the p arm of the X chromosome(specifically, Xp11.23). A member of the FOX protein family, FOXP3 appears to function as a master regulator in the development and function of regulatory T cells. While the precise control mechanism has not yet been established, FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription.

Gene Full Name: forkhead box P3

Gene ID: 50943

UniProt: Q9BZS1

Pathways: Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation