SLC6A1 antibody (AA 23-215) (Fluoro647)

Catalog No. ABIN7992319

The Rabbit Polyclonal anti-SLC6A1 antibody is suitable to detect SLC6A1 in samples from Human, Rat and Mouse. It has been validated for FACS.

Quick Overview for SLC6A1 antibody (AA 23-215) (Fluoro647) (ABIN7992319)

Target: SLC6A1 (GAT1) (GABA Transporter 1 (GAT1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC6A1 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-SLC6A1 Antibody (Fluoro647)

Binding Specificity: AA 23-215

Purpose: Anti-GAT1/SLC6A1 Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human SLC6A1 shares 98.4% amino acid (aa) sequence identity with both mouse,rat SLC6A1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GAT1/SLC6A1 recombinant protein (Position: A23-A215). Human SLC6A1 shares 98.4% amino acid (aa) sequence identity with both mouse and rat SLC6A1.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SLC6A1

Target: SLC6A1 (GAT1) (GABA Transporter 1 (GAT1))

Alternative Name: SLC6A1

Background:

Background: GABA transporter 1 (GAT1), also known as sodium- and chloride-dependent GABA transporter 1, is a protein that in humans is encoded by the SLC6A1 gene. GABA Transporter 1 uses Na+ and Cl- to create a gradient, which removes or adds GABA to extracellular spaces in the cerebrum and cerebellum. The stoichiometry for GABA Transporter 1 is 2 Na+: 1 Cl-: 1 GABA. The activity of GAT1 is largely dependent on the presence of Na+, while Cl- assists by increasing the ability for GAT-1 to uptake GABA.

Gene Full Name: solute carrier family 6 member 1

Gene ID: 6529

UniProt: P30531