SLC6A1 antibody (AA 23-215)

Catalog No. ABIN7992320

The Rabbit Polyclonal anti-SLC6A1 antibody (ABIN7992320) specifically detects SLC6A1 in WB and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for SLC6A1 antibody (AA 23-215) (ABIN7992320)

Target: SLC6A1 (GAT1) (GABA Transporter 1 (GAT1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC6A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Carrier-free

Product Details anti-SLC6A1 Antibody

Binding Specificity: AA 23-215

Purpose: Anti-GAT1/SLC6A1 Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human SLC6A1 shares 98.4% amino acid (aa) sequence identity with both mouse,rat SLC6A1.

Characteristics: Anti-GAT1/SLC6A1 Antibody. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GAT1/SLC6A1 recombinant protein (Position: A23-A215). Human SLC6A1 shares 98.4% amino acid (aa) sequence identity with both mouse and rat SLC6A1.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SLC6A1

Target: SLC6A1 (GAT1) (GABA Transporter 1 (GAT1))

Alternative Name: SLC6A1

Background:

Background: GABA transporter 1 (GAT1), also known as sodium- and chloride-dependent GABA transporter 1, is a protein that in humans is encoded by the SLC6A1 gene. GABA Transporter 1 uses Na+ and Cl- to create a gradient, which removes or adds GABA to extracellular spaces in the cerebrum and cerebellum. The stoichiometry for GABA Transporter 1 is 2 Na+: 1 Cl-: 1 GABA. The activity of GAT1 is largely dependent on the presence of Na+, while Cl- assists by increasing the ability for GAT-1 to uptake GABA.

Gene Full Name: solute carrier family 6 member 1

Molecular Weight: 67 kDa

Gene ID: 6529

UniProt: P30531