GALNS antibody (AA 181-289) (Fluoro550)

Catalog No. ABIN7992335

The Fluoro550-conjugated Rabbit Polyclonal anti-GALNS antibody (ABIN7992335) specifically detects GALNS in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GALNS antibody (AA 181-289) (Fluoro550) (ABIN7992335)

Target: GALNS (Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GALNS antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-GALNS Antibody (Fluoro550)

Binding Specificity: AA 181-289

Purpose: Anti-GALNS Antibody Fluoro550 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human GALNS recombinant protein (Position: Y181-N289).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for GALNS

Target: GALNS (Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS))

Alternative Name: GALNS

Background:

Background: N-acetylgalactosamine-6-sulfatase is an enzyme that, in humans, is encoded by the GALNS gene. This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder.

Gene Full Name: galactosamine (N-acetyl)-6-sulfatase

Gene ID: 2588

UniProt: P34059

Pathways: Glycosaminoglycan Metabolic Process