GGCT antibody (AA 25-188)

Catalog No. ABIN7992584

The Rabbit Polyclonal anti-GGCT antibody (ABIN7992584) specifically detects GGCT in WB, ELISA and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GGCT antibody (AA 25-188) (ABIN7992584)

Target: GGCT (gamma-Glutamylcyclotransferase (GGCT))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GGCT antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-GGCT Antibody

Binding Specificity: AA 25-188

Purpose: Anti-GGCT Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human GGCT shares 86.4% amino acid (aa) sequence identity with mouse GGCT.

Characteristics: Anti-GGCT Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GGCT recombinant protein (Position: N25-L188). Human GGCT shares 86.4% amino acid (aa) sequence identity with mouse GGCT.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GGCT

Target: GGCT (gamma-Glutamylcyclotransferase (GGCT))

Alternative Name: GGCT

Background:

Background: The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Full Name: gamma-glutamylcyclotransferase

Molecular Weight: 21 kDa

Gene ID: 79017

UniProt: O75223