GJA4 antibody (AA 95-148)

Catalog No. ABIN7992661

The Rabbit Polyclonal anti-GJA4 antibody is suitable to detect GJA4 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and FACS.

Quick Overview for GJA4 antibody (AA 95-148) (ABIN7992661)

Target: GJA4 (Gap Junction Protein, alpha 4, 37kDa (GJA4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJA4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-GJA4 Antibody

Binding Specificity: AA 95-148

Purpose: Anti-GJA4 Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human GJA4 shares 90.7%,92.6% amino acid (aa) sequence identity with mouse,rat GJA4,respectively.

Characteristics: Anti-GJA4 Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GJA4 recombinant protein (Position: H95-R148). Human GJA4 shares 90.7% and 92.6% amino acid (aa) sequence identity with mouse and rat GJA4, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg /1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GJA4

Target: GJA4 (Gap Junction Protein, alpha 4, 37kDa (GJA4))

Alternative Name: GJA4

Background:

Background: Gap junction alpha-4 protein, also known as Connexin-37 or Cx37, is a protein that in humans is encoded by the GJA4 gene. This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction.

Gene Full Name: gap junction protein alpha 4

Molecular Weight: 37 kDa

Gene ID: 2701

UniProt: P35212

Pathways: Cell-Cell Junction Organization