GATA5 antibody (AA 1-397) (Fluoro550)

Catalog No. ABIN7992974

The Fluoro550-conjugated Rabbit Polyclonal anti-GATA5 antibody (ABIN7992974) specifically detects GATA5 in FACS. The antibody is reactive with Human samples.

Quick Overview for GATA5 antibody (AA 1-397) (Fluoro550) (ABIN7992974)

Target: GATA5 (GATA Binding Protein 5 (GATA5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GATA5 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-GATA5 Antibody (Fluoro550)

Binding Specificity: AA 1-397

Purpose: Anti-GATA5 Antibody Fluoro550 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human GATA5 shares 75% amino acid (aa) sequence identity with mouse GATA5.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GATA5 recombinant protein (Position: M1-A397). Human GATA5 shares 75% amino acid (aa) sequence identity with mouse GATA5.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for GATA5

Target: GATA5 (GATA Binding Protein 5 (GATA5))

Alternative Name: GATA5

Background:

Background: Transcription factor GATA-5, also named GATAS or GATA5, is a protein that in humans is encoded by the GATA5 gene. It is mapped to 20q13.33. The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity. In addition, the expression of GATA5 increased in a human colon cancer cell line within 2 hours of exposure to sodium butyrate, which induces differentiation.

Gene Full Name: GATA binding protein 5

Sequence Similarities: Contains 2 GATA-type zinc fingers.

Gene ID: 140628

UniProt: Q9BWX5