GINS2 antibody (AA 1-185) (Biotin)

Catalog No. ABIN7993158

This Rabbit Polyclonal antibody specifically detects GINS2 in ELISA, WB and IHC. It exhibits reactivity toward Human.

Quick Overview for GINS2 antibody (AA 1-185) (Biotin) (ABIN7993158)

Target: GINS2 (GINS Complex Subunit 2 (Psf2 Homolog) (GINS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GINS2 antibody is conjugated to Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GINS2 Antibody (Biotin)

Binding Specificity: AA 1-185

Purpose: Anti-PSF2/GINS2 Antibody Biotin Conjugated

Predicted Reactivity: Human GINS2 shares 92.4% amino acid (aa) sequence identity with mouse GINS2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PSF2/GINS2 recombinant protein (Position: M1-F185). Human GINS2 shares 92.4% amino acid (aa) sequence identity with mouse GINS2.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GINS2

Target: GINS2 (GINS Complex Subunit 2 (Psf2 Homolog) (GINS2))

Alternative Name: GINS2

Background:

Background: DNA replication complex GINS protein PSF2 is a protein that in humans is encoded by the GINS2 gene. The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4, MIM 610611), Psf1 (GINS1, MIM 610608), Psf2, and Psf3 (GINS3, MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.

Gene Full Name: GINS complex subunit 2

Gene ID: 51659

UniProt: Q9Y248

Pathways: DNA Replication, Synthesis of DNA