Glucose-6-Phosphate Dehydrogenase antibody (AA 315-515) (Fluoro594)

Catalog No. ABIN7993459

The Rabbit Polyclonal anti-Glucose-6-Phosphate Dehydrogenase antibody is suitable to detect Glucose-6-Phosphate Dehydrogenase in samples from Human and Mouse. It has been validated for FACS.

Quick Overview for Glucose-6-Phosphate Dehydrogenase antibody (AA 315-515) (Fluoro594) (ABIN7993459)

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glucose-6-Phosphate Dehydrogenase antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-Glucose-6-Phosphate Dehydrogenase Antibody (Fluoro594)

Binding Specificity: AA 315-515

Purpose: Anti-Glucose 6 Phosphate Dehydrogenase/G6PD Antibody Fluoro594 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human G6PD shares 95%,96% amino acid (aa) sequences identity with mouse,rat G6PD,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human G6PD recombinant protein (Position: E315-L515). Human G6PD shares 95% and 96% amino acid (aa) sequences identity with mouse and rat G6PD, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Glucose-6-Phosphate Dehydrogenase

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Alternative Name: G6PD

Background:

Background: Glucose-6-phosphate dehydrogenase, also known as G6PD or G6PDH, is an enzyme that in humans is encoded by the G6PD gene. It is mapped to Xq28. G6PD plays a key role in the production of ribose 5-phosphate and the generation of NADPH in the hexose monophosphate pathway. Because this pathway is the only NADPH-generation process in mature red cells, which lack the citric adid cycle, a genetic deficiency of G6PD is often associated with adverse physiologic effects. It has been found that aldosterone decreased G6PD expression and activity, resulting in increased oxidant stress and decreased nitric oxide levels, similar to what is observed in G6PD-deficient endothelial cells.

Gene Full Name: glucose-6-phosphate dehydrogenase

Sequence Similarities: Belongs to the glucose-6-phosphate dehydrogenase family.

Gene ID: 2539

UniProt: P11413

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones