GBA3 antibody (AA 17-469) (FITC)

Catalog No. ABIN7993548

This Rabbit Polyclonal antibody specifically detects GBA3 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for GBA3 antibody (AA 17-469) (FITC) (ABIN7993548)

Target: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBA3 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-GBA3 Antibody (FITC)

Binding Specificity: AA 17-469

Purpose: Anti-GBA3 Antibody FITC Conjugated

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GBA3 recombinant protein (Position: Q17-L469).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for GBA3

Target: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Alternative Name: GBA3

Background:

Background: Cytosolic beta-glucosidase, also known as cytosolic beta-glucosidase-like protein 1, is a beta-glucosidase (EC 3.2.1.21) enzyme that in humans is encoded by the GBA3 gene. The protein encoded by this gene is a cytosolic enzyme that can hydrolyze several types of glycosides. The enzyme has its highest activity at neutral pH and is predominantly expressed in human liver, kidney, intestine, and spleen. This gene is a polymorphic pseudogene, with the most common allele being the functional allele that encodes the full-length protein. Some individuals contain a single nucleotide polymorphism that results in a premature stop codon in the coding region, and therefore this allele is pseudogenic due to the failure to produce a functional full-length protein. Alternative splicing of this gene results in multiple transcript variants.

Gene Full Name: glucosylceramidase beta 3 (gene/pseudogene)

Gene ID: 57733

UniProt: Q9H227