Glucuronidase beta antibody (AA 122-575) (Fluoro594)

Catalog No. ABIN7993569

This Rabbit Polyclonal antibody specifically detects Glucuronidase beta in FACS. It exhibits reactivity toward Mouse and Rat.

Quick Overview for Glucuronidase beta antibody (AA 122-575) (Fluoro594) (ABIN7993569)

Target: Glucuronidase beta (GUSB) (Glucuronidase, beta (GUSB))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glucuronidase beta antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-Glucuronidase beta Antibody (Fluoro594)

Binding Specificity: AA 122-575

Purpose: Anti-beta glucuronidase/Gusb Antibody Fluoro594 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse beta glucuronidase/Gusb recombinant protein (Position: R122-E575).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Glucuronidase beta

Target: Glucuronidase beta (GUSB) (Glucuronidase, beta (GUSB))

Alternative Name: Gusb

Background:

Background: Beta-glucuronidases are members of the glycosidase family of enzymes that catalyze breakdown of complex carbohydrates. This gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. Alternative splicing results in multiple transcript variants. There are many pseudogenes of this locus in the human genome.

Gene Full Name: glucuronidase, beta

Gene ID: 110006

UniProt: P12265

Pathways: Glycosaminoglycan Metabolic Process