Glutaredoxin 1 antibody (AA 1-106) (HRP)

Catalog No. ABIN7994091

This Rabbit Polyclonal antibody specifically detects Glutaredoxin 1 in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for Glutaredoxin 1 antibody (AA 1-106) (HRP) (ABIN7994091)

Target: Glutaredoxin 1 (GRX1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutaredoxin 1 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Glutaredoxin 1 Antibody (HRP)

Binding Specificity: AA 1-106

Purpose: Anti-Glutaredoxin 1/GLRX Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Glutaredoxin 1/GLRX recombinant protein (Position: M1-Q106).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Glutaredoxin 1

Target: Glutaredoxin 1 (GRX1)

Alternative Name: GLRX

Background:

Background: Glutaredoxin-1 is a protein that in humans is encoded by the GLRX gene. This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.

Gene Full Name: glutaredoxin

Gene ID: 2745

UniProt: P35754

Pathways: Cell RedoxHomeostasis