Glutaredoxin 1 antibody (AA 1-106)

Catalog No. ABIN7994095

The Rabbit Polyclonal anti-Glutaredoxin 1 antibody is suitable to detect Glutaredoxin 1 in samples from Human. It has been validated for WB, IHC, ELISA, IF, ICC and FACS.

Quick Overview for Glutaredoxin 1 antibody (AA 1-106) (ABIN7994095)

Target: Glutaredoxin 1 (GRX1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutaredoxin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-Glutaredoxin 1 Antibody

Binding Specificity: AA 1-106

Purpose: Anti-Glutaredoxin 1/GLRX Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Glutaredoxin 1/GLRX Antibody. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Glutaredoxin 1/GLRX recombinant protein (Position: M1-Q106).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Glutaredoxin 1

Target: Glutaredoxin 1 (GRX1)

Alternative Name: GLRX

Background:

Background: Glutaredoxin-1 is a protein that in humans is encoded by the GLRX gene. This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.

Gene Full Name: glutaredoxin

Molecular Weight: 12 kDa

Gene ID: 2745

UniProt: P35754

Pathways: Cell RedoxHomeostasis