Glutaredoxin 2 antibody (AA 1-164) (FITC)

Catalog No. ABIN7994101

The Rabbit Polyclonal anti-Glutaredoxin 2 antibody is suitable to detect Glutaredoxin 2 in samples from Human and Mouse. It has been validated for FACS.

Quick Overview for Glutaredoxin 2 antibody (AA 1-164) (FITC) (ABIN7994101)

Target: Glutaredoxin 2 (GRX2)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutaredoxin 2 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-Glutaredoxin 2 Antibody (FITC)

Binding Specificity: AA 1-164

Purpose: Anti-GRX2/GLRX2 Antibody FITC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GRX2/GLRX2 recombinant protein (Position: M1-Q164).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Glutaredoxin 2

Target: Glutaredoxin 2 (GRX2)

Alternative Name: GLRX2

Background:

Background: GLRX2 (Glutaredoxin-2) also known as Glutaredoxin-2, mitochondrial or GRX2, is a protein that in humans is encoded by the GLRX2 gene. Glutaredoxins (e.g., GLRX) are a family of glutathione-dependent hydrogen donors that participate in a variety of cellular redox reactions. By sequence analysis, Lundberg et al. (2001) and Gladyshev et al. (2001) identified the GLRX2 gene within a clone mapping to chromosome 1q31.2-q31.3. Lundberg et al. (2001) determined that the GLRX2 gene contains 5 exons spanning about 9.6 kb. The GLRX2B transcript uses a first exon (exon 1B) located upstream from the first exon used by the GLRX2A transcript (exon 1A), suggesting that alternative splicing generates the isoforms. Lundberg et al. (2001)assayed reductase activity in recombinant proteins of both GLRX2 isoforms. They found that both have GSH-dependent dehydroascorbate reductase activity and 2-hydroxyethyl disulfide reductase activity.

Gene Full Name: glutaredoxin 2

Gene ID: 51022

UniProt: Q9NS18

Pathways: Cell RedoxHomeostasis