GLRX3 antibody (AA 89-177) (Fluoro488)

Catalog No. ABIN7994120

The Fluoro488-conjugated Rabbit Polyclonal anti-GLRX3 antibody (ABIN7994120) specifically detects GLRX3 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GLRX3 antibody (AA 89-177) (Fluoro488) (ABIN7994120)

Target: GLRX3 (Glutaredoxin 3 (GLRX3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLRX3 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-GLRX3 Antibody (Fluoro488)

Binding Specificity: AA 89-177

Purpose: Anti-TXNL2/GLRX3 Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived human TXNL2 recombinant protein (Position: L89-S177). Human TXNL2 shares 93.3%,94.4% amino acid (aa) sequence identity with mouse,rat TXNL2,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human TXNL2 recombinant protein (Position: L89-S177). Human TXNL2 shares 93.3% and 94.4% amino acid (aa) sequence identity with mouse and rat TXNL2, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for GLRX3

Target: GLRX3 (Glutaredoxin 3 (GLRX3))

Alternative Name: GLRX3

Background:

Background: Glutaredoxin-3 is a protein that in humans is encoded by the GLRX3 gene. This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene.

Gene Full Name: glutaredoxin 3

Gene ID: 10539

UniProt: O76003

Pathways: Cell RedoxHomeostasis