GSTM2 antibody (Middle Region)

Catalog No. ABIN7994337

This Rabbit Polyclonal antibody specifically detects GSTM2 in WB. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for GSTM2 antibody (Middle Region) (ABIN7994337)

Target: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSTM2 antibody is un-conjugated

Application: Western Blotting (WB)

Grade: Carrier-free

Product Details anti-GSTM2 Antibody

Binding Specificity: Middle Region

Purpose: Anti-GSTM2 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Mouse GSTM2 shares 72% amino acid (aa) sequence identity with both mouse,rat GSTM2.

Characteristics: Anti-GSTM2 Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human GSTM2. Mouse GSTM2 shares 72% amino acid (aa) sequence identity with both mouse and rat GSTM2.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GSTM2

Target: GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))

Alternative Name: GSTM2

Background:

Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.

Gene Full Name: glutathione S-transferase mu 2

Molecular Weight: 26 kDa

Gene ID: 2946

UniProt: P28161

Pathways: Negative Regulation of Transporter Activity