GSTM3 antibody (AA 93-206) (APC)

Catalog No. ABIN7994356

The Rabbit Polyclonal anti-GSTM3 antibody is suitable to detect GSTM3 in samples from Human and Mouse. It has been validated for FACS.

Quick Overview for GSTM3 antibody (AA 93-206) (APC) (ABIN7994356)

Target: GSTM3 (Glutathione S-Transferase mu 3 (Brain) (GSTM3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSTM3 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-GSTM3 Antibody (APC)

Binding Specificity: AA 93-206

Purpose: Anti-GSTM3 Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human GSTM3 recombinant protein (Position: E93-Q206).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for GSTM3

Target: GSTM3 (Glutathione S-Transferase mu 3 (Brain) (GSTM3))

Alternative Name: GSTM3

Background:

Background: Glutathione S-transferase M3 (brain), also known as GSTM3, is an enzyme which in humans is encoded by theGSTM3 gene. Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins.

Gene Full Name: glutathione S-transferase mu 3

Gene ID: 2947

UniProt: P21266