GSTP1 antibody (AA 2-210) (HRP)

Catalog No. ABIN7994377

The Rabbit Polyclonal anti-GSTP1 antibody is suitable to detect GSTP1 in samples from Human, Mouse and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for GSTP1 antibody (AA 2-210) (HRP) (ABIN7994377)

Target: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSTP1 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-GSTP1 Antibody (HRP)

Binding Specificity: AA 2-210

Purpose: Anti-GST3/GST pi/GSTP1 Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human GST3 shares 85%,86% amino acid (aa) sequences identity with mouse,rat GST3,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GST3 recombinant protein (Position: P2-Q210). Human GST3 shares 85% and 86% amino acid (aa) sequences identity with mouse and rat GST3, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GSTP1

Target: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Alternative Name: GSTP1

Background:

Background: Glutathione S-transferases pi (GSTP1), also known as GST3, is an enzyme that in humans is encoded by the GSTP1 gene. This gene is mapped to 11q13.2. GSTP1 has 7 exons and 6 introns contained within approximately 2.8 kilobases. GSTP1 belongs to Glutathione S-transferases (GSTs) which are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 presents in all tissues and cells, with the exception of red cells, in which only erythrocyte GST (GSTe) is observed. What's more, GSTP1 is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.

Gene Full Name: glutathione S-transferase pi 1

Sequence Similarities: Belongs to the GST superfamily. Pi family.

Gene ID: 2950

UniProt: P09211

Pathways: Cellular Response to Molecule of Bacterial Origin