CD235b/GYPB antibody (AA 43-91) (APC)

Catalog No. ABIN7994642

The APC-conjugated Rabbit Polyclonal anti-CD235b/GYPB antibody (ABIN7994642) specifically detects CD235b/GYPB in FACS. The antibody is reactive with Human samples.

Quick Overview for CD235b/GYPB antibody (AA 43-91) (APC) (ABIN7994642)

Target: CD235b/GYPB (GYPB) (Glycophorin B (GYPB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD235b/GYPB antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-CD235b/GYPB Antibody (APC)

Binding Specificity: AA 43-91

Purpose: Anti-GYPB Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GYPB recombinant protein (Position: Q43-A91).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CD235b/GYPB

Target: CD235b/GYPB (GYPB) (Glycophorin B (GYPB))

Alternative Name: GYPB

Background:

Background: Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97 % sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. Alternate splicing results in multiple transcript variants.

Gene Full Name: glycophorin B (MNS blood group)

Gene ID: 2994

UniProt: P06028