GZMM antibody (C-Term) (Fluoro488)

Catalog No. ABIN7995088

The Rabbit Polyclonal anti-GZMM antibody is suitable to detect GZMM in samples from Human. It has been validated for FACS.

Quick Overview for GZMM antibody (C-Term) (Fluoro488) (ABIN7995088)

Target: GZMM (Granzyme M (Lymphocyte Met-Ase 1) (GZMM))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GZMM antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-GZMM Antibody (Fluoro488)

Binding Specificity: C-Term

Purpose: Anti-Granzyme M/GZMM Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human Granzyme M,GZMM shares 85.7% amino acid (aa) sequence identity with rat Granzyme M,GZMM.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Granzyme M/GZMM. Human Granzyme M/GZMM shares 85.7% amino acid (aa) sequence identity with rat Granzyme M/GZMM.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for GZMM

Target: GZMM (Granzyme M (Lymphocyte Met-Ase 1) (GZMM))

Alternative Name: GZMM

Background:

Background: Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: granzyme M

Gene ID: 3004

UniProt: P51124