GCHFR antibody (AA 2-84) (PE)

Catalog No. ABIN7995578

The PE-conjugated Rabbit Polyclonal anti-GCHFR antibody (ABIN7995578) specifically detects GCHFR in FACS. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for GCHFR antibody (AA 2-84) (PE) (ABIN7995578)

Target: GCHFR (GTP Cyclohydrolase I Feedback Regulator (GCHFR))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCHFR antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-GCHFR Antibody (PE)

Binding Specificity: AA 2-84

Purpose: Anti-GCHFR Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GCHFR recombinant protein (Position: P2-E84).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for GCHFR

Target: GCHFR (GTP Cyclohydrolase I Feedback Regulator (GCHFR))

Alternative Name: GCHFR

Background:

Background: GTP cyclohydrolase 1 feedback regulatory protein is an enzyme that in humans is encoded by the GCHFR gene. GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide.

Gene Full Name: GTP cyclohydrolase I feedback regulator

Gene ID: 2644

UniProt: P30047